The type of measurement or value determined by the assay.
Allowable values: pAC50, pEC50, pIC50, pKd, pKi
Standard IUPAC International Chemical Identifier (InChI) descriptor key for the cofactor.
InChI, the IUPAC International Chemical Identifier, by Stephen R Heller, Alan McNaught, Igor Pletnev, Stephen Stein and Dmitrii Tchekhovskoi, Journal of Cheminformatics, 2015, 7:23
Examples: BNOCDEBUFVJMQI-REOHCLBHSA-N
Simplified molecular-input line-entry system (SMILES) descriptor for the cofactor.
Weininger D (February 1988). "SMILES, a chemical language and information system. 1. Introduction to methodology and encoding rules". Journal of Chemical Information and Modeling. 28 (1): 31-6.
Weininger D, Weininger A, Weininger JL (May 1989). "SMILES. 2. Algorithm for generation of unique SMILES notation", Journal of Chemical Information and Modeling. 29 (2): 97-101.
The chemical component definition identifier for the cofactor.
Examples: 0Z3, CD9
The cofactor description.
Examples: A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
The cofactor name.
Examples: Menadione
The BIRD definition identifier for the cofactor.
Examples: PRD_000010
Identifier for the cofactor assigned by the resource.
Examples: CHEMBL1987, DB00170
Mechanism of action describes the biochemical interaction through which the cofactor produces a pharmacological effect.
Examples: Menadione (vitamin K3) is involved as a cofactor in the posttranslational gamma-carboxylation of glutamic acid residues of certain proteins i n the body. These proteins include the vitamin K-dependent coagulation factors II (prothrombin), VII (proconvertin), IX (Christmas factor), X (Stuart factor), protein C, protein S, protein Zv and a growth-arrest-specific factor (Gas6).
A flag to indicate the cofactor is a structural neighbor of this entity.
Allowable values: N, Y
Patent numbers reporting the pharmacology or activity data.
PubMed identifiers for literature supporting the pharmacology or activity data.
Resource providing target and cofactor data.
Allowable values: ChEMBL, DrugBank, Pharos
Version of the information distributed by the data resource.
Examples: V4_0_2
Identifier for the target assigned by the resource.
Examples: P00734, CHEMBL2242
Generated using TypeDoc
The value measured or determined by the assay.
Examples: null